Conference: Superelectrophilic Activation in Superacid
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Research interest

Superacid Chemistry – Fluorine Chemistry – Bioactive Compounds Synthesis

 

Research career

  • 2015 Professor Ship position – University of Poitiers – IC2MP – Team organic synthesis
  • 2004 Assistant Professor – University of Poitiers – IC2MP – Team organic synthesis – superacid group
  • 2003-2004 Post-doctoral fellow, Oxford University, UK. Supervisor: Pr. V. Gouverneur (Marie-Curie Fellowship)
  • 1999-2002 PhD in organic chemistry University of Poitiers – UMR 6514
    « Réactions en milieu superacide: fluoration et hydroxylation de composés organiques azotés, Réarrangement d’alkaloïdes de Quinquina ». Supervisors: Pr. J-C. Jacquesy

 

Teaching

University of Poitiers: Fundamental and Applied Science Faculty Master 1/2 Organic Synthesis

 

Management/Supervision/Administrative duties

  • Member of the management committee of the Institute of chemistry UMR 7285 (2012–to date)
  • Co-Leader of the organic synthesis team of the Institute of chemistry UMR 7285 (2018-to date) 13 permanent researchers
  • Leader of the superacid group of IC2MP (2012–to date) 5 researchers / 2 Pdoc / 4 PhD students / 2 engineers
  • Member of editorial boards: « Journal of Enzyme Inhibition and Medicinal Chemistry » and « Current Enzyme Inhibition »

 

Current Funding

  • @rtMolecule society – 126 k€ : 2015-2018
  • BBraun society – 97 k€ : 2018-2019
  • ANR (National research agency) – 407 k€ (ORGASUP/SWEETCAT projects) : 2015-2019
  • EU FEDER 1B : SUPERDIV Project – 330 k€ : 2017-2019
  • Javlor® anti-cancer agent Royalties – 75 k€ : 2018
  • CNRS PICS Program – 15 k€ : 2017-2019

 

Scientific production

  • 47 publications / 2 book chapters
  • 53 invited conferences: 27 in national and international symposiums and 26 in laboratory seminars

 

Five representative publications

  1. “Evidence of Phosphonium-Carbenium Dication Formation in a Superacid: Precursor to Fluorinated Phosphine Oxides” U. Castelli, J-F. Lohier, I. Drukenmüller, A. Mingot, C. Bachman, C. Alayrac, J. Marrot, K. Stierstorfer, A. Kornath, A-C. Gaumont, S. Thibaudeau Angew. Chem. Int. Ed. 2019, 58, 1355-1360
  2. “Superacid-catalyzed trifluoromethylthiolation of aromatic amines” L. J. C. Bonazaba Milandou, H. Carreyre, S. Alazet, G. Greco, A. Martin-Mingot, C. Nkounkou Loumpangou, J-M. Ouamba, F. Bouazza, T. Billard, S. Thibaudeau. Angew. Chem. Int. Ed. 2017, 56, 169 –172 (inside cover)
  3. “HF-induced intramolecular C-arylation and C-alkylation/fluorination of 2-aminoglycopyranoses” N. Probst, A. Martin, J. Désiré, A. Mingot, J. Marrot, Y. Blériot, S. Thibaudeau Org. Lett. 2017, 19, 1040-1043.
  4. “Catching elusive glycosyl cations in a condensed phase with HF/SbF5” A.Martin, A. Arda, J. désiré, A. Martin-Mingot, N. Probst, P. Sinaÿ, J. Jimenez-Barbero, S. Thibaudeau, Y. Blériot. Nat. Chem. 2016, 8, 186-191.
  5. “Keteniminium ion-initiated cascade cationic polycyclisation” B.Theunissen, B. Métayer, N. Henry, G. Compain, J. Marrot, A. Martin-Mingot, S. Thibaudeau, G. Evano. J. Am. Chem. Soc. 2014, 136, 12528-12531 (cover + highlight).

 

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